A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10236
Swiss-prot Accession numberQ7YRC3 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta 4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismMacropus eugenii (Tammar wallaby)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Diprotodontia; Macropodidae; Macropus.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
Function Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight5037
References1  PubMed abstract 15008146
Domain NameThymosin  
Hormone NameThymosin beta-4
Mature Hormone SequenceSDKPDMGEIQKFNKSKLKKTETQEKNPLPSKETIEQEKQAGES
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number10237
Swiss-prot Accession numberQ7YRC3 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta 4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismMacropus eugenii (Tammar wallaby)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Diprotodontia; Macropodidae; Macropus.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
Function Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase
Protein Length44 Amino acids
Molecular weight5037
References1  PubMed abstract 15008146
Domain NameThymosin  
Hormone NameHematopoietic system regulatory peptide
Mature Hormone SequenceSDKP
Position of mature hormone in Pre-Hormone protein4 Residues from position (2-5)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number10488
Swiss-prot Accession numberP68126 (Sequence in FASTA format)
DescriptionCholecystokinin (CCK).
Source organismMacropus eugenii (Tammar wallaby)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Diprotodontia; Macropodidae; Macropus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length8 Amino acids
Molecular weight1064
References1  PubMed abstract 3375140
Domain NameN/A
Hormone NameCholecystokinin
Mature Hormone SequenceDYMGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (1-8)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated